DF-UpWhite, Sepiwhite™ MSH, Skin Brightening

INCI Name: Undecylenoyl phenylalanine
Other Name: SepiWhite MSH
CAS#: 175357-18-3

DF-UpWhite is a natural skin-lightening agent made of amino acids. It is an excellent skin lightener and brightener for all skin types and ethnicities, promoting a more uniform, radiant complexion with results in as little as seven days.

Several studies have shown its skin-brightening and dark-spot-fading effects. When combining 1% Sepiwhite with 5% niacinamide, 83% of volunteers reported a more radiant complexion, 73% pigment reduction in age spots, 100% even complexion, and a lighter skin tone in 8 weeks. 

With Sepiwhite alone, volunteers reported 24% pigment reduction in just a few days, and 73% in seven days.

Its skin-brightening effects doubled in studies using 0.2% Sepiwhite MSH and 2% Ascorbyl Glucoside.

Studies have shown that Sepiwhite can be combined with 5% niacinamide in lotion. Volunteers reported a reduction in hyperpigmentation after 8 weeks of usage.

Key Benefits

• Combats the appearance of hyperpigmentation.
• Promotes an even and brighter skin tone
• Reduces the number and color of age spots
• Non-phototoxic

Applications

• Radiant complexion
• Anti-aging spots
• Skin-lightening products, such as moisturizers, lotions, and makeup

Ingredient Information:

• INCI: Undecylenoyl phenylalanine
• Recommended usage: 0.2-2%
• Water-soluble at pH 7.0; otherwise insoluble in water. Soluble in alcohol and oil.
• Must be melted for use (best in the oil phase of formula at 80°C/176°F). Optimal pH 4-5 or 6.2-7 for best incorporation into formulas.
• When using a commercial lotion/cream base, first melt and dissolve it in warm oil (80°C/176°F) before adding it to the base. Otherwise, it will form lumps and will not dissolve.

Formulating Guidelines

• Use 0.2% with another brightener; otherwise, use up to 2% in the heated water or heated oil phase of a formulation at more than 60°C (140°F).
• In a product with pH 5 or lower, incorporate into any type of formula.
• In products above pH 5.0 but below 6.2, incorporate with up to 20% ethanol. This is not the ideal pH range for this ingredient.
• In products with pH 6.2 or higher, incorporation into any formula type is possible.

Compatibility & Stability

• Excellent stability in cosmetic products with no expected color or odor changes
• Compatible with formulas containing AHA and kojic acid (pH below 5)
• Compatible with formulas containing arbutin, hydroquinone, niacinamide, and those above pH 7
• Compatible with sunscreens
• Suitable for aqueous, hydroalcoholic, or hydroglycolic formulas
• Suitable for clear, colorless formulas

Recommended Usage Rate: 0.2 - 2%
Solubility: Water-soluble at pH 7, otherwise insoluble in water. Miscible in water. Soluble in alcohol and oil.
pH (1% solution in water): 4.0
Country of Origin: China
Shelf Life: 1 year if stored in a cool, dark place

Like all of our ingredients, Sepwhite MSH can only be used externally at the recommended rate.