Phytosphingosine - None water soluble

Phytosphingosine, Non-water soluble. 

A healthy skin barrier is key to maintaining healthy skin, and whether a skincare product will be effective or not.

One of the primary functions of the skin barrier is to prevent transepidermal water loss (TEWL). It is also the basic goal for skincare. Maintaining the skin's moisture at an optimal level enables all the skin's biochemical and physiological activities to occur at an ideal level. Well-hydrated skin is not only essential for maintaining a supple, smooth, and radiant skin texture, but it also helps minimize pores, fine lines, and wrinkles, and even slows down the skin aging process through its self-defense mechanism. 

In skincare, the moisture level directly affects the result of active skincare.  Unfortunately, almost all skin concerns affect the barrier function, including those associated with aging skin. A skincare strategy should always include both barrier restoration and targeted treatment of specific skin concerns. 

Phytosphingosine is a natural skin barrier lipid, the precursor of ceramides. It enhances the barrier function, locking in moisture in the skin. It also functions as an antimicrobial and anti-inflammatory agent, beneficial for conditions such as acne, eczema, and psoriasis. It reinforces the skin's protective barrier, protecting the skin against environmental pollutants and irritants. It is always considered a beneficial multiple skin ingredient by experts.

Formulate tips:

Although it is often referred to as oil-soluble, it actually has an amphiphilic structure that can attract both water and oil under the right conditions. At room temperature, it doesn't dissolve in either of them. It will dissolve in oil/lipid at much higher temperatures (≥90°C). Its water solubility will be significantly improved when a specific acidic agent, such as lactic acid, is used to lower the pH. 

This ingredient can be challenging for beginners to handle. Chemists can easily handle it. Using ethanol as a solvent to dissolve this ingredient may be an excellent choice for beginners

INCI: 554-62-1
Appearance: Fine White powder
Odor: Characteristic
Recommended usage: 0.2-0.5%
Solubility: Insoluble in water. Insoluble in lipids at room temperature. Soluble in ethanol and methanol.

Document:

Specification Sheet
SDS